Rejuran in Korea: The Skin Healer Injection That’s More Than Just Anti-Aging
Rejuran is one of Korea’s most trusted skin boosters — not just for aging, but for healing. Discover why this polynucleotide injection is transforming how dermatologists repair and restore skin from within.
What Is Rejuran and How Does It Work?
Rejuran is an injectable skin booster made from polynucleotides (PN), a DNA-derived molecule extracted from salmon — yes, really. Why salmon? Its PN structure is biologically similar to humans, making it safe and highly biocompatible.
Once injected into the dermis, Rejuran works by improving the skin’s healing response, increasing collagen production, and repairing cellular damage. Unlike fillers or Botox, Rejuran doesn’t “fill” — it tells your skin to heal itself.
What Skin Concerns Does It Treat?
Rejuran is ideal for:
- Acne scars and rough texture
- Dullness and loss of elasticity
- Enlarged pores
- Skin weakened by lasers or over-exfoliation
- Early fine lines
Korean clinics often recommend Rejuran for skin that feels “thin,” “fragile,” or “tired-looking.” It's also a go-to post-procedure recovery treatment thanks to its regenerative effects.
What to Expect During and After the Procedure
Rejuran is delivered via microinjections into the dermis using a fine needle or injector gun. The procedure takes about 15–20 minutes and is often done with numbing cream. Expect to see tiny bumps (“mosquito bites”) immediately after — these usually fade within 24 hours.
Some mild swelling, pinpoint bruising, or warmth may last 1–2 days. It’s best to avoid alcohol, sauna, or intense workouts right after. Most clients start seeing a noticeable glow and firmness around the 2-week mark, with optimal results after 3–4 sessions spaced 2–3 weeks apart.
Rejuran vs. Other Skin Boosters
Rejuran is often compared to other skin boosters like hyaluronic acid (e.g. Juvederm Volite) or exosome treatments. Here’s how they differ:
- Rejuran: Stimulates regeneration, best for long-term skin health and structure
- HA-based boosters: Excellent for immediate hydration and plumpness
- Exosomes: Signal proteins for targeted repair and glow
Many Korean dermatologists combine Rejuran with hyaluronic acid boosters for synergistic results — healing plus hydration.
Dr. Beau's Note
I often recommend Rejuran to patients whose skin feels tired — not just dry or aging, but depleted. It’s one of the few treatments that actually improves skin quality over time. If you’re looking to rebuild your skin, not just boost it, Rejuran is where you start.
